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Marie Evangelista Selected Research

GDC-0425

5/2017Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors.

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Marie Evangelista Research Topics

Disease

18Neoplasms (Cancer)
04/2023 - 10/2009
3Breast Neoplasms (Breast Cancer)
01/2017 - 11/2012
1Neoplasm Metastasis (Metastasis)
04/2023
1Hypertension (High Blood Pressure)
12/2022
1Lung Neoplasms (Lung Cancer)
01/2022
1Hypoxia (Hypoxemia)
10/2018
1Fever (Fevers)
05/2017
1Nausea
05/2017
1Neutropenia
05/2017
1Syncope (Fainting)
05/2017
1Thrombocytopenia (Thrombopenia)
05/2017
1Dyspnea (Shortness of Breath)
05/2017
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2017
1Osteosarcoma (Osteogenic Sarcoma)
01/2017
1Colorectal Neoplasms (Colorectal Cancer)
01/2017
1Melanoma (Melanoma, Malignant)
11/2013
1Triple Negative Breast Neoplasms
11/2012
1Glioma (Gliomas)
09/2008
1Hydrocephalus (Hydrocephaly)
08/2005

Drug/Important Bio-Agent (IBA)

5Phosphotransferases (Kinase)IBA
01/2022 - 10/2009
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018 - 01/2017
3Biomarkers (Surrogate Marker)IBA
05/2017 - 04/2012
2ErbB Receptors (EGF Receptor)IBA
01/2022 - 04/2012
2Lactic Acid (Lactate)FDA LinkGeneric
10/2018 - 11/2012
2EnzymesIBA
10/2018 - 01/2018
2GemcitabineFDA Link
05/2017 - 10/2013
1B7-H1 AntigenIBA
04/2023
1serum P-component (CIt)IBA
04/2023
1Proteins (Proteins, Gene)FDA Link
01/2023
1Antihypertensive Agents (Antihypertensives)IBA
12/2022
1Pyruvic Acid (Pyruvate)IBA
10/2018
1Lactate DehydrogenasesIBA
10/2018
1Lactate Dehydrogenase 5IBA
10/2018
1Glucose (Dextrose)FDA LinkGeneric
10/2018
1Oxygen (Dioxygen)IBA
10/2018
1Ligases (Synthetase)IBA
01/2018
1gamma-glutamylcysteineIBA
01/2018
1cobimetinibIBA
01/2018
1GlutaminaseIBA
01/2018
1Glutathione (Reduced Glutathione)IBA
01/2018
1Alanine Transaminase (SGPT)IBA
05/2017
1GDC-0425IBA
05/2017
1Checkpoint Kinase 1IBA
05/2017
1A-Form DNA (A-DNA)IBA
01/2017
1mirdametinibIBA
01/2017
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2016
1GNE-140IBA
10/2016
1Small Interfering RNA (siRNA)IBA
10/2016
1Mechanistic Target of Rapamycin Complex 1IBA
04/2016
1Aldehyde DehydrogenaseIBA
07/2014
13,4-dihydroxybenzohydroxamic acidIBA
03/2014
1Hormones (Hormone)IBA
03/2014
1TamoxifenFDA LinkGeneric
03/2014
1Temozolomide (Temodar)FDA LinkGeneric
11/2013
1GNE-783IBA
11/2013
1Estrogens (Estrogen)FDA Link
11/2012
1lactate dehydrogenase 1 (LDH1)IBA
11/2012
1Phenobarbital (Luminal)FDA Link
11/2012
1Progesterone Receptors (Progesterone Receptor)IBA
11/2012
1Formaldehyde (Formol)FDA Link
04/2012
1Insulin (Novolin)FDA Link
10/2009
1Tyrosine (L-Tyrosine)FDA Link
10/2009
1EphA1 Receptor (Eph Receptor)IBA
10/2009
1Transcription Factors (Transcription Factor)IBA
09/2008
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
08/2005

Therapy/Procedure

6Therapeutics
01/2023 - 11/2012
3Drug Therapy (Chemotherapy)
04/2023 - 04/2012
1Immunotherapy
04/2023
1Treatment Delay
07/2014